The Journal of Organic Chemistry 是有机化学领域的经典期刊，报道与有机化学理论和实践有关的各类综合研究，有近90年的历史。所发表的论文聚焦各种全新、已知化合物的设计与合成方法研究，涉及主题包括催化、光化学、化学生物学和医药化学、天然产物的分离与全合成、糖化学、肽与蛋白质、功能有机材料等。
The Journal of Organic Chemistry 编辑团队根据文章的质量、关注度、重要性及其潜在的持续影响力等方面对投稿进行评估，得到审稿人尤为正面评价的论文被精选为精选论文(Featured Articles)。本期虚拟专刊共收录了JOC 在2021年发表的16篇最具特色的精选论文，欢迎阅读。
JOC Featured Articles
Deciphering Reactivity and Selectivity Patterns in Aliphatic C–H Bond Oxygenation of Cyclopentane and Cyclohexane Derivatives
Teo Martin, Marco Galeotti, Michela Salamone, Fengjiao Liu*, Yanmin Yu, Meng Duan, K. N. Houk*, and Massimo Bietti*
J. Org. Chem. 2021, 86, 15, 9925-9937
DOI: 10.1021/acs.joc.1c00902
Photocatalytic Radical Ortho-Dearomative Cyclization: Access to Spiro[4.5]deca-1,7,9-trien-6-ones
Wuheng Dong*, Yao Yuan, Caiyun Liang, Feng Wu, Siyuan Zhang, Xiaomin Xie, and Zhaoguo Zhang*
J. Org. Chem. 2021, 86, 5, 3697-3705
DOI: 10.1021/acs.joc.0c02477
Regioselective C–H Alkenylation and Unsymmetrical Bis-olefination of Heteroarene Carboxylic Acids with Ruthenium Catalysis in Water
Anup Mandal, Ratnadeep Bera, and Mahiuddin Baidya*
J. Org. Chem. 2021, 86, 1, 62-73
DOI: 10.1021/acs.joc.0c02215
Reagent and Catalyst Capsules: A Chemical Delivery System for Reaction Screening and Parallel Synthesis
Niginia Borlinghaus, Johannes Kaschel, Johanna Klee, Vanessa Haller, Jasmin Schetterl, Stephanie Heitz, Tanja Lindner, Justin D. Dietrich, Wilfried M. Braje*, and Anais Jolit*
J. Org. Chem. 2021, 86, 2, 1357-1370
DOI: 10.1021/acs.joc.0c02576
Synthesis of Aminomethylene-gem-bisphosphonates Containing an Aziridine Motif: Studies of the Reaction Scope and Insight into the Mechanism
Thomas Cheviet and Suzanne Peyrottes*
J. Org. Chem. 2021, 86, 4, 3107-3119
DOI: 10.1021/acs.joc.0c02434
Enantioselective Total Synthesis of Nitraria Alkaloids: (+)-Nitramine, (+)-Isonitramine, (−)-Isonitramine, and (−)-Sibirine via Asymmetric Phase-Transfer Catalytic α-Allylations of α-Carboxylactams
Jewon Yang, Yohan Park, Sehun Yang, Geumwoo Lee, Min Woo Ha, Mi-hyun Kim, Suckchang Hong, and Hyeung-geun Park*
J. Org. Chem. 2021, 86, 6, 4375-4390
DOI: 10.1021/acs.joc.0c02573
Flow Chemistry under Extreme Conditions: Synthesis of Macrocycles with Musklike Olfactoric Properties
Alexandra Seemann, Johannes Panten, and Andreas Kirschning*
J. Org. Chem. 2021, 86, 20, 13924-13933
DOI: 10.1021/acs.joc.1c00663
NMR Quantification of Hydrogen-Bond-Accepting Ability for Organic Molecules
Mira Milic, Karina Targos, Magda Tellez Chavez, Madison A. M. Thompson, Julia J. Jennings, and Annaliese K. Franz*
J. Org. Chem. 2021, 86, 9, 6031-6043
DOI: 10.1021/acs.joc.0c02876
Exploiting Continuous Processing for Challenging Diazo Transfer and Telescoped Copper-Catalyzed Asymmetric Transformations
Daniel C. Crowley, Thomas A. Brouder, Aoife M. Kearney, Denis Lynch, Alan Ford, Stuart G. Collins, and Anita R. Maguire*
J. Org. Chem. 2021, 86, 20, 13955-13982
DOI: 10.1021/acs.joc.1c01310
Multistep Continuous Flow Synthesis of Stavudine
Cloudius R. Sagandira, Faith M. Akwi, Mellisa B. Sagandira, and Paul Watts*
J. Org. Chem. 2021, 86, 20, 13934-13942
DOI: 10.1021/acs.joc.1c01013
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